The Drug Trial That Went Wrong: Emergency At The Hospital (Medical Documentary) - Real Stories

  • Опубликовано: 11 апр 2018
  • On Monday 13 March 2006, eight healthy young men took part in a clinical trial of an experimental drug known as TGN1412. The drug was intended to treat leukaemia and had already been successfully tested on monkeys but never on humans.
    It should have been a routine clinical trial but it soon spiraled into one of the most infamous medical emergencies in recent British history.
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Комментарии • 6 129

  • NiceMuslimLady
    NiceMuslimLady 4 минуты назад

    7:41 What could go wrong? Here, drink this unknown liquid...what could go wrong, right?

  • Jacklyn Timms
    Jacklyn Timms 3 часа назад

    and thats why I would not sign up to test drugs.....

  • therellnevab
    therellnevab 6 часов назад

    So they do a trial on human beings and you do it 10x faster in terms of the procedure and administering the drug in the system way quicker then that of the trial on the monkeys....trials are done over a period of days not in one setting....they were careless PERIOD!!!!

  • whywar1986
    whywar1986 22 часа назад

    Glad i only stuck to tasting different types of orange juice or not blind tasting anything at all in order to do surveys to get money no matter how broke i am i will not try something like this.

  • Simon K.
    Simon K. День назад

    nice documentary but honestly this could have been 30m with the same amount of information

  • Mia Chia
    Mia Chia День назад

    I love how everyone’s in extreme pain in the beginning and one guy is just looking around and watching people throw up and scream in pain and just has a face like “oh, I think I’m about to die soon”

  • English Cloud
    English Cloud День назад

    Is the CCTV footage real or a reconstruction?

  • interSpeces Family
    interSpeces Family День назад

    Can you just imagine what animals that are tested on must go through?! Its not like THEY volunteered and in this case what did the primates that they tested this drug on, previous to this incident go through. WTF😡 Sick, filthy bastards.

  • Sister blister
    Sister blister День назад

    Never ever volunteer for anything! 😱

  • lazy gizmo
    lazy gizmo День назад

    I hate to be that guy. But something like this "experimental" test. You know they had to sign a written contract that risk are involved. They knew the risk and took it anyway for financial compensation. They got no one to blame but themselves. They make new medicine everyday. Their experimental failure will aid future research.

  • Huntin boss11
    Huntin boss11 День назад

    This is just like I am legend starring will smith

  • Nao Shadowpaws
    Nao Shadowpaws День назад

    Should have scrubbed the trial after all four dosed subjects became ill. Run saline wide open, flush the drug from their system and label that one a failure. With side effects that extreme you cant market that

  • Bloog Foog
    Bloog Foog День назад

    They should just use prisoners on death row or who are sentenced to life in prison for stuff like this

  • diego002 Boscan
    diego002 Boscan День назад

    hope they got a lot of money for it.

  • T -Gay
    T -Gay День назад

    Instead of having innocent people sign up, people who are on line for the death penalty should have to sign up for this.

  • Shvnobi
    Shvnobi 2 дня назад

    thats how they set you up. a whole nother resident evil episode smh

  • Hayina Thgirw
    Hayina Thgirw 2 дня назад

    How much is 2000 pounds in American money?

  • Dylan W
    Dylan W 2 дня назад +1

    I don't care if the reward is one billion dollars I'm never taking one of these tests no no no

  • Erin Laemmle
    Erin Laemmle 2 дня назад

    𝐏𝐬𝐲𝐜𝐡𝐨𝐩𝐚𝐭𝐡𝐢𝐜 𝐝𝐨𝐜𝐭𝐨𝐫𝐬!

  • It'sYOb0IWilLY mR. kRAbSs
    It'sYOb0IWilLY mR. kRAbSs 2 дня назад

    1. Maybe it works on specific people
    2.Or maybe they got too much of the drug. I don't know

  • Jaime Hudson
    Jaime Hudson 2 дня назад


  • Aidan D
    Aidan D 2 дня назад

    This is what the next zombie movie is going to be based on


    I am glad all the man is okay survived. 💓💓💓💓


    Oh my god.... Poor Ryan.... I hope he is okay.... 🙏🙏🙏🙏 💓💓💓💓

  • Ashley Gant
    Ashley Gant 3 дня назад +1

    can we talk about the scientist contradicting himself how have the same cell like monkeys, but it didnt react the same? we are nit like the monkeys then or are we?

  • Nilly K
    Nilly K 3 дня назад

    Poor monkeys.

  • Marcus Mcmillan
    Marcus Mcmillan 3 дня назад

    Did they still get paid?

  • Sunny Flower
    Sunny Flower 3 дня назад

    32:00 finally someone's family was informed!!!!!!

  • S P P
    S P P 3 дня назад

    Imagine what animals endure

  • space nerd
    space nerd 3 дня назад

    wait but was ryan ok?

  • Christina Brown
    Christina Brown 3 дня назад

    This all started the day before I was born!woow

  • The President Of Logic
    The President Of Logic 4 дня назад

    Do you guys think maybe the drug could have worked but they gave the patients wayyyy too much? Like, a lot of medications save lives but if you overdose your body can't handle it...

  • art by nitil
    art by nitil 4 дня назад

    All subs have watched this video ..

  • Katt Bee
    Katt Bee 4 дня назад

    I feel ill just watching this. Wow.

  • Big B Kenobi
    Big B Kenobi 4 дня назад

    Here is why you dont make yourself a medical guinea pig for money...

  • green bean
    green bean 5 дней назад

    This hit too close to home. I'd done 2 drug trials before, and I was very careful; both times were on medication that was already used in humans for years. (One was just a new delivery system, in a nasal spray, and the other was for a different dose I think?) Both of those went well, and the money was great ($8000 for one of them). So then I relaxed my standards a bit and signed up for that had only been used in humans once before I think. It was also an infusion iv one. I was the only person that had a negative reaction, and it was really scary. When the guy talked about seeing this totally unknown liquid going into your arm, that gave me shivers. But yeah, I remember that when it hit me, I couldn't speak or react, I started sweating profusely but was freezing cold (my feet never sweat, and they were drenched) and apparently I was staring blankly for 15minutes, but to me I could have sworn it was 1 minute. All these doctors rushed over and I just remember my vision got weird, it was like the room just flipped upside down. but not really... just like, everything was suddenly not where it was supposed to be. Like if your head suddenly snapped all the way back. And this happened a few times, the room just..flipping.
    Luckily it slowly started to wear off and I returned to normal, but it was terrifying. The other patients told me they were terrified too (there were barriers between us but we were all in the same room. I knew some of them, and they said I just went silent and they heard the drs calling my name over and over. They thought I was dying or something). The worst part was I remember the drs were more just...observing me. Like they were checking to see if I was ok, but also standing around and making notes and checking the time (cuz it's important to write down exactly when things happen in studies). I felt very much like an animal that was being observed for their gain, not like a human in a medical possible-emergency.
    That was the last one I ever did, and ever will do. I still worry about that sometimes, like when i think of having kids, will it affect them, whatever this substance was? Or will I develop some sort of cancer later or something? Not worth it in my opinion, never again.

  • Phorest The phorest
    Phorest The phorest 5 дней назад

    So 6 were affected, two were ok, 1 lost fingers and toes what about the other three, did they die?

  • Kim Lowe
    Kim Lowe 5 дней назад


  • Catherine Li
    Catherine Li 5 дней назад

    those people are heroes. I would never do it though. I'm not as empathetic.

  • Oscar Chapman
    Oscar Chapman 5 дней назад

    Pharmacy ad...

  • Alex Harrison
    Alex Harrison 5 дней назад

    Patient 007 James Bond

  • Dustin Littleton
    Dustin Littleton 5 дней назад

    Guy dying “sir how are you doing”

  • EJ Ioane
    EJ Ioane 5 дней назад

    instead of experimenting on the general public...why cant they use any new drugs on prison inmates instead?

  • Nicky Lyons
    Nicky Lyons 5 дней назад

    As someone with zero medical experience, I can't believe they administered the drug to each test subject at such short intervals!!

  • Blkchevy98
    Blkchevy98 6 дней назад

    The people signed up fully knowing that it's the first human trials. They knew there were risks and accepted the terms. Blame is thrown on everybody!
    Where is the volunteers responsibility for their own actions part?
    You took the risk and gambled & it back fired! Sorry for what you & your families went through but YOU must take & accept responsibility as well.

  • Starla Hall
    Starla Hall 6 дней назад

    Animal testing is cruel.

  • Tom Wootton
    Tom Wootton 7 дней назад

    I think it’s just a bit not thought through well enough if they are testing a drug that focuses on cancer cells on non cancerous people . Clearly the drug will attack normal body cells if there are no cancer cells therefore they were getting multiple organ failure

  • David Allen
    David Allen 7 дней назад

    Someone was responsible for that! DO me a favour . You were responsible. You rented out your body for cash. No one forced you. Like a hooker on the streets who also rents their body for cash. It was your choice.

  • Nyx_Ares
    Nyx_Ares 7 дней назад

    In the trial it was injected into the bloodstream 10 times quicker than it had been to the monkeys..... GEE I wonder why it failed, wtf? What kind of doctors are these?..

  • watchman
    watchman 7 дней назад

    In hindsight, if I was the placebo dude I would've been glad not to have gotten sick but pissed I got no money

  • Michele Evans
    Michele Evans 7 дней назад

    Two questions...when did they ever notify your families and without any of you having leukemia, I don’t understand how healthy individuals would be good candidates to test this drug on.

  • you`re wrong
    you`re wrong 8 дней назад

    fvck this

  • Lucy Alvarez
    Lucy Alvarez 8 дней назад

    How come it was only his fiancé that could visit and not the other patients family?

  • sebastian langley
    sebastian langley 8 дней назад

    i really wanted to know how much they got paid, i bet it was like 400,000 or something decent

  • Kayleigh
    Kayleigh 8 дней назад

    My dad was involved in a drug trial a few years ago. I was quite nervous for him. He was fine and the drug worked fine, though. I have considered doing this as the trials pay a fair amount. This has turned me off now 😐

  • Malaika N
    Malaika N 8 дней назад

    Fam they could of died they should be paid like wayyyy more than £2000-£3000

  • just me
    just me 8 дней назад

    Feel bad for everyone involved, just terrible. Glad there was survivors.

  • 小倩
    小倩 8 дней назад

    I like the guy reading he is cool

  • 小倩
    小倩 8 дней назад

    The guy reading the book is like what’s happening he was so interested into the book he feels no pain.....

  • Dawkins Varner
    Dawkins Varner 8 дней назад

    this happened on my 1st birthday.

  • HelloSatan
    HelloSatan 9 дней назад +1

    Testing cancer drugs sounds like it's hardcore regardless! Anyone who's experienced cancer first hand or from looking after someone knows what I mean! 2 grand is Not enough to test a cancer drug!

  • Miranda Scott
    Miranda Scott 9 дней назад

    Omg poor ryan

  • Miss B_Perfectionist
    Miss B_Perfectionist 9 дней назад

    Lots of respect to the men involved in this testing and lots of respect to doctors and staff involved who tried to do their best🙏🙏🙏❤️

  • mia!
    mia! 9 дней назад +1

    shouldn't they do drug tests to people on death row

  • Adriana Stache
    Adriana Stache 9 дней назад

    So Ryan died?

  • Fab Elger
    Fab Elger 9 дней назад

    52:56 and they actually confirmed the exact opposite of what most of you say here...the point was that the,, docking station" on the monkeys for this drug is different in that it needs a,, catalyst" to react in this way. Humans have this,, catalyst" on the docking station which wasn't you could have given the monkey 1000 times the dosage and they wouldn't have gotten problems BUT you could have given a human 10 THOUSAND times less and still it would have been the same reaction......nobody could have predicted it happening 50:45 Look it up...this is the independent guy from the court trial.

  • Fab Elger
    Fab Elger 9 дней назад

    They DID NOT administer MORE in LESS time! DO THE MATH! It was 500 times less than what they gave the monkeys...if you take 500 grains of salt in 5 ml of water the dosage is 100 per 1 ml. the humans got 1 grain of salt in the WHOLE 5 ml. No matter HOW QUICK you administer those 5ml...the dosage nor the amount of grain salt per time x can be higher than what the monkeys got IN ANY WAY. They DID not administer more nor quicker.

  • Fab Elger
    Fab Elger 9 дней назад

    soo?? THE DRUG WORKS!?? it CAN cure cancer..but as you were healthy the immune reaction turned against the only thing they could find?? I HOPE this drug IS NOT ABANDONED because of this unprecedented problem.

  • Jade Bell
    Jade Bell 9 дней назад

    I’m not a feminist but they should’ve had a women try the drug too, if their were any participants

    • ALevel12RemiHasAppeared
      ALevel12RemiHasAppeared 7 дней назад

      Jade Bell it would have most likely had a worse effect on women as they specifically mentioned about the effect on their reproductive system

    • Jade Bell
      Jade Bell 9 дней назад

      1.?? 2. I said they should’ve had women do it too before I even heard what he said about the reproductive system, but still a women might’ve had a different outcome. 3. When you have nothing to say you just correct grammar😂

    • mia!
      mia! 9 дней назад +1

      1. do you even know the meaning of feminist? so you believe women are lesser than men. sounds fake, but ok
      2. they specifically mentioned women shouldn't do the drug because it may have an effect on their reproductive system
      3. it's there not their

  • Sarah Choi
    Sarah Choi 9 дней назад

    This reminds me of when I got stevens-Johnson’s from my anti seizure meds. Life is great

  • Alyssa Napier
    Alyssa Napier 10 дней назад

    44 minutes in explains the exact reason why this should have happened in the first place

  • Maafu Lolohea
    Maafu Lolohea 10 дней назад

    guys, if this is a real story, then why is there a camera there, camera not allow filming a guy in drug laying down crazy.

    • mia!
      mia! 9 дней назад's a dramatic re-enactment LMAO

  • lemons limes
    lemons limes 10 дней назад

    And of course crazy animal rights activists jump into the comments bitching about the monkeys being tested. I don't even think they watched the video, just wanted to virtue signal. A bunch of men nearly die but think of the monkeys!

  • Taylor zzstu Starnes
    Taylor zzstu Starnes 10 дней назад

    I kind of realized it was the amount of the drug and how fast it was going into their blood stream in the first half before they even discovered that. It seemed crazy the amount in that syringe!

  • M smith
    M smith 10 дней назад

    This should be done on prisoners serving life sentences

  • Laura Gomes
    Laura Gomes 10 дней назад +1

    I'm never taking part a drug trial in my life now, oh my god

  • Unikish
    Unikish 10 дней назад

    Did anyone die because the other 2 we're not shown on the interview inbetween times¿

  • Nakia Hoffmann
    Nakia Hoffmann 10 дней назад


    • ALevel12RemiHasAppeared
      ALevel12RemiHasAppeared 7 дней назад

      Levi Glocks really? I think it's kinda interesting but I like all the medical stuff so it might just be me.

  • LeighAnn Middleton
    LeighAnn Middleton 10 дней назад +1

    I got a fricken Tik Tok add..... .-.

  • Clashking
    Clashking 11 дней назад

    16:09 "how we doing David"? Oh I dunno doc looks to have had better days...

  • Jason Flanagan
    Jason Flanagan 11 дней назад

    UK Documentary - Very linear, follows a narrative in sequential order.
    US Documentary - Dramatic music, repeating the same scene over and over and interviews with people divorced from reality.

  • Patricia Chalmers
    Patricia Chalmers 11 дней назад

    I wonder if the volunteers got their two thousand pounds?.

  • Rayner Gemma
    Rayner Gemma 12 дней назад

    I actually remember this. I was 16 at the time :( so sad very sad

  • aldonza
    aldonza 12 дней назад

    overdose + mass hysteria-esque effects

  • That Guy With the Pointlessly Long Username That You Are Wasting Your Time Reading Right Now

    Sounds like this inspired the reboot of the Planet of the Apes movies. “Miracle medicine that works for apes, unknown and fatal results for humans”

  • Carol Coates
    Carol Coates 13 дней назад +2

    Instead of using animals and decent human beings, use 'lifers' and paedophiles for research!

  • Laila Robinson
    Laila Robinson 13 дней назад

    Is Ryan dead??

  • WakingOHIOMama 91
    WakingOHIOMama 91 13 дней назад

    Too bad there was NO acknowledgement of the terrible mishandling of this trial, it never should have gone to human trials apparently. So sad that this happened.

  • WakingOHIOMama 91
    WakingOHIOMama 91 13 дней назад

    A government agency passing the buck??? NOOOOOOOOO NOT EVER.

  • WakingOHIOMama 91
    WakingOHIOMama 91 13 дней назад

    FIVE TIMES FASTER. DEAR LORD, that infusion should have been stopped by the 2nd hour. The cures for so many diseases are far worse than dying from the diseases themselves.

  • WakingOHIOMama 91
    WakingOHIOMama 91 14 дней назад

    WOW it's crazy how we put so much trust in the government that people would put themselves through this.

  • WakingOHIOMama 91
    WakingOHIOMama 91 14 дней назад

    I would have ripped my iv out and demanded that they stop the trial immediately!

    • ALevel12RemiHasAppeared
      ALevel12RemiHasAppeared 7 дней назад

      WakingOHIOMama 91 that wouldn't have helped the people who have received the drug. Also, ripping out your iv is probably a stupid thing to do

  • WakingOHIOMama 91
    WakingOHIOMama 91 14 дней назад

    Pure bile?! Liver failure? Jesus it's crazy people died!! I'm so sad that this happened.

  • WakingOHIOMama 91
    WakingOHIOMama 91 14 дней назад

    My GOD. They should have dc'd this IMMEDIATELY

  • WakingOHIOMama 91
    WakingOHIOMama 91 14 дней назад

    I just can't believe nothing like this has never happened before, I can't believe it at all!! I mean the very words drug trial are scary themselves.

  • Top Cat
    Top Cat 14 дней назад +1

    Straight to the lawyers for money

  • Space Cookie
    Space Cookie 14 дней назад

    What happened to David? It said that he was in the ICU for much longer than the other men, had to have his fingers and foot amputated, suffered from many infections etc. But when did he start recovering? I assume that he didn’t die...

    • ALevel12RemiHasAppeared
      ALevel12RemiHasAppeared 7 дней назад

      Space Cookie no one died and I thought ryan had his fingers amputated

  • BB Mythic Gaming
    BB Mythic Gaming 14 дней назад

    Did Ryan die?

  • Ksloozy Doo
    Ksloozy Doo 14 дней назад

    Bet you would never do this again! Most patients who have spent any length of time in a hospital are also aware that multiple mistakes on every ward in every hospital are made each week (probably meaning millions a week) and many people become sick from them. While apologies are be made, these appear to be almost never documented. Many patients also don't receive medicines on time and sometimes not at all due to staff shortages. Personally I knew of 2 patients who ecen died because of hospital errors only. A hospital is the most dangerous place people can end up in, period, and should be avoided as much as possible if a patient isn't already on his death bed!

  • Nevlin Thirta
    Nevlin Thirta 14 дней назад

    Is just call bargain u baragain money and life that what u bargain